Ester Tempos

Ester Vazquez


Ester, prior to her industry leap and the inception of TEMPoS, honed her skills as a postdoctoral fellow at the MRC-Laboratory of Molecular Biology (Cambridge, UK), immersing herself in cryo-EM and cancer biology. She boasts a PhD in Biology from the University of Santiago de Compostela (Spain), followed by post-doctoral training in prion structure using cryo-EM at the University of Alberta (Canada).


Sevillano AM. Fernández-Borges N, Younas N, Wang F, Elezgarai SR, Bravo S, Vázquez-Fernández E, Rosa I, Eraña H, Gil D, Veiga S, Vidal E, Erickson-Beltran ML, Guitian E, Silva CJ, Nonno R, Ma J, Castilla J, Requena JR.

Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.

PLoS Pathog. 14(1):e1006797



Vázquez-Fernández E, Vos MR, Afanasyev P, Cebey L, Sevillano AM, Vidal E, Rosa I, Renault L, Ramos A, Peters PJ, van Heel M, Young HS, Requena JR, Wille H.

The structural architecture of an infectious mammalian prion using electron cryomicroscopy.

PLoS Pathog. 12(9):e1005835



Vázquez-Fernández E, Alonso J, Pastrana MA, Ramos A, Stitz L, Vidal E, Dynin I, Petsch B, Silva CJ, Requena JR.

Structural organization of mammalian prions as probed by limited proteolysis.

PLoS One. 7(11):e50111

Sajnani G, Silva CJ, Ramos A, Pastrana MA, Onisko BC, Erickson ML, Antaki EM, Dynin I, Vázquez-Fernández E, Sigurdson CJ, Carter JM, Requena JR.

PK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrP.

PLoS Pathog. 8(3):e1002547